In order to participate in the seminar, on November 20 after 4:45 pm (UTC+7) you should connect to the Zoom conference via the following link https://zoom.us/j/93473879731 or manually using the Zoom conference ID 934 7387 9731.
Population genomics is an interdisciplinary science, which combines genetics, mathematics and computer science. It studies the structure of populations and the history of their development based on genetic data. Events such as changes in population size, separation and mixing of populations leave marks on genomes. By reducing the cost of DNA sequencing and processing speed, we have obtained an unprecedented variety of genomic data.
In the first part of the talk, we will discuss the main mathematical population models used in genomics. We will also discuss the main methods of population analysis of genetic data that are based on them. Then we will look at examples of how population models can be applied to experimental data. In particular, the talk will present the results of a study of the SARS-CoV-2 coronavirus pandemic in Russia, when viral sequences become available for analysis in almost real time. This allowed us to estimate the number of imports of the virus into Russia, as well as the sources of these imports. We also studied the local outbreak of COVID-19 at the Vreden's Institute of Traumatology and Orthopedics and showed that the virus was brought in there independently 2-3 times.